Each Ampoule of 2 mi contains:
- Thiamine HCI (B1). 200 mg
- Riboflavine Sodium Phosphate (B2) 4 mg.
- Pyridoxine HCI (B6), 100 mg
- Cyanocobalamine (B12). 1000 mcg
- Lidocaine HCI. 10 mg
- Benzyl alcohol, Polysorbate 80, NaOH/ HCI & water for injection
- Neurimax is indicated for prevention and treatment of deficiency of vitamin B1, B6, B2 and B12 and their prophylaxis eg. in neurological and other disorders associated with disturbance of the metabolic function influenced by B complex vitamins
Contraindication & warning:
- -This product contains Benzyl alcohol which is potentially toxic when administered locally to neural tissue
- * This product is contraindicated for use in premature infants because the formulation contains Benzyl alcohol
Pregnancy, nursing mothers & pediatric use Do not administer injections preserved with Benzyl alcohol to neonates, infants pregnant women or nursing mothers,
Benzyl alcohol has been associated with serious adverse events & death, particularly in pediatric patients Injections preservative free should be used in these populations
Neumax injection shall not be used in cases under suspicion of hypersensitivity to any of the above ingredients
Dosage and directions for use:
- Neurimax ampoules injected intramuscularly (deep intragluteal), in severe cases, one ampule is even daily until acute symptoms subside
- For milder cases and follow up therapy 2 to 3 ampoules per week
- Patients treated with L-Dope should not take high doses of pyridoxine and thus not Neurimax as it reduces the effect of L-Dopa
- In individual cases sweating, tachycardia and skin reactions accomplishes with
- itching and urticaria have been described in rare cases hypersensitivity reactions may occur. e.g. after parenteral application of vitamin B1
- exanthemes , difficulties to breathe and conditions of shock may occur.
- In individual cases drug induced eczema and urticaria has been reported after parenteral vitamin B12 application
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