HISTAZINE -1 TAB

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HISTAZINE -1 TAB

15.50 EGP

  • Brand: HISTAZINE -1
  • Country of manufacture: Egypt
  • Size: 10 capsules
  • Type: Capsules

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Description

ACTIVE-INGREDIENT OF HISTAZINE -1 TAB

each tablet contains : active ingredient : cetirizine dihydrochloride 10 mg

INDICATION OF HISTAZINE1 TAB

cetirizine is indicated for the relief of nasal and ocular symptoms of seasonal and perennial allergic rhinitis . Cetirizine is indicated for the relief of symptoms of chronic idopathic uriticaria .

DOSAGE OF HISTAZINE-1 TAB

Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet

Ask your pharmacist or doctor for help if you do not understand the instructions on the box .

The recommended dose is : –

  • children aged from 2 to 6 years : 2.5 mg twice daily or 5 mg once daily .
  • children aged from 6 to 12 years : 5 mg twice daily .
  • adults and adolescents over 12 years of age : 10 mg once daily .
  • For histazine tablets : 1/2 tablet (=5 mg) = 5 mg , 1 tablet ( = 10 mg ) .
  • elderly subjects : the data dose not suggest that the dose needs to be reduced in elderly subjects provided that the renal function is normal – patients with moderate to severe renal impairment : there is no data to document the efficacy / safety ratio in patients with renal impairment .
  • since cetirizine is mainly eliminated via renal route , in cases where no alternative treatment can be used , the dosing intervals must be individualized according to renal function .
  • refer to the following table and adjust the dose as indicated .
  • to use this dosing table , an estimate of the patient’s creatinine clearance (cl cr) in ml/min is needed .
  • the cl cr (ml/min ) may be estimated from serum creatinine (mg/dl ) determination using the following formula : 1-normal : >- 80 ml/min :- 10 mg once daily .2-mild :50-79 ml/min :- 10 mg once daily . 3-moderate :30-49 ml/min :- 5 mg once daily . 4-severe :
  • OVER-DOSAGE OF HISTAZINE-1 TAB

  • symptoms observed after an overdose of cetirizine are mainly associated with CNS effects or with effects that could suggest an anticholinergic effect .
  • Adverse events reported after an intake of at least 5 times the recommended daily dose are : confusion , sedation , somnolence , stupor , tachycardia , tremor , and urinary retention . – management .
  • there is no known specific antidote to cetirizine .
  • should overdose occur , symptomatic or supportive treatment is recommended .
  • gastric lavage should be considered following ingestion of a short occurrance .
  • cetirizine is not effectively removed by dialysis .

CONTRA-INDICATION OF HISTAZINE-1 TAB

  • hypersensitivity to the active substance , any of the excipients , hydroxyzine or any piperazine derivatives .
  • patients with severe renal impairment at less than 10 ml/min creatinine clearance .
  • patients with rare herediaritary problems of galactose intolerance , the lapp lactase deficiency or glucose – glactose malabsorption should not take histazine tablets .

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